Nhảy đến nội dung
x

Laboratory of Theoretical and Computational Biophysics

1. Introduction

Laboratory of Theoretical and Computational Biophysics (TCB) is founded by Ton Duc Thang University in order to investigate the physical insights of biological system behaviors at the atomic and electronic level. The understanding widely apply to resolve numerous interdisciplinary problems involving molecular modeling, drug design, biofuel, material and environment, etc.

2. Mission and vision

The TCB targets to resolve urgency problems in biophysics such as:
- Investigating the conformations of disorder proteins using extensive molecular dynamics simulations.
- Estimating the Gibbs free energy difference of binding between biomolecules.
- Determining the physical insights of metalloproteins such as deoxyhypusine dydroxylase and polysaccharide monooxygenases.
- Discovering tremendous potential inhibitors for Aβ oligomers, neuraminidase, HIV protease, and acetylcholinesterase, etc.

3. Research topics

- Quantum chemical investigations of metalloproteins
- Folding/Misfolding of disorder proteins
- Free energy calculations
- Synthetic materials

4. Current members

COMCHEM_Ngo_Son_Tung.jpg

Dr. Son Tung Ngo

Positions:

• Head of Laboratory of Theoretical and Computational Biophysics, Ton Duc Thang University
• Assistant professor at Ton Duc Thang University

Areas of expertise: Computational Biophysics, Free energy Calculations, Protein folding/misfolding, Computer-aided drug design, and Metalloproteins

Research track record (until October of 2018):

• ISI papers: 23
• Total ISI Citations:334
• ISI H-index:10
• At most 5 top journals:
- Coordination Chemistry Reviews (Impact factor: 14.5)
- Journal of Chemical Information and Modeling (Impact factor: 3.8)
- Journal of Physical Chemistry B (Impact factor: 3.2)
- ACS Chemical Neuroscience (Impact factor: 4.2)
- Journal of Computational Chemistry (Impact factor: 3.2)

DEMASTED_Nguyen_Van_Luong.jpg

Dr. Nguyen Van Luong

Positions:

• Member of Laboratory of Theoretical and Computational Biophysics, Ton Duc Thang University

Areas of expertise: Optimal control theory, nonsmooth analysis, optimization, fixed point theory and applications

DEMASTED_Tran_Phuoc_Duy.jpg

Dr. Tran Phuoc Duy

Position: Member of Laboratory of Theoretical and Computational Biophysics, Ton Duc Thang University

Areas of expertise: Computational Biophysics and Bioinformatics

COMCHEM_Tran_Thi_Thuy_Linh.jpg

Dr. Tran Thi Thuy Linh

Position: Member of Laboratory of Theoretical and Computational Biophysics, Ton Duc Thang University

Areas of expertise: Computer Aided Drug Design, Molecular Modeling

COMCHEM_Nguyen_Thi_Mai.JPG

Msc. Nguyen Thi Mai

Position: Member of Laboratory of Theoretical and Computational Biophysics, Ton Duc Thang University

Areas of expertise: Computational chemistry

5. Former members (name, title, picture)

6. Publications (ISI or Scopus only)

7. Contact: