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Bone and Muscle Research Group (BMRG)

1. Introduction

The BMRg is a newly created research group of Ton Duc Thang University. The BMR group was established with the support from the University’s Foundation for Science and Technology Development (FOSTECT). The main research focus of the Group is osteoporosis, osteoarthritis, sarcopenia, and obesity-related problems.

The BMRg brought together scientists from various disciplines, including clinical medicine, clinical epidemiology, genetics, and basic research, who have special interest in bone research.

2. Mission and vision

Our vision is to build the Bone and Muscle Research Group as a leading center for research into osteoporosis and bone diseases, and through which we contribute to better health in Vietnam and internationally.

Our mission is to discover, impart and translate knowledge pertaining to biological mechanisms, etilogical risk factors and genetic factors into prevention and treatment of osteoporosis and osteoarthritis.

3. Research topics

• Bone architecture in osteoporosis and osteoarthritis: longitudinal study.

• Osteoarthritis: Interaction between environmental factors and genetic.

• Genetic determinants of the association between osteoporosis and osteoarthritis.

4. Current members


Dr. Tuan V. Nguyen


• Director of Bone and Muscle Research Group, Ton Duc Thang University, Ho Chi Minh City, Vietnam

• Visiting professor & Senior Scientific Advisor, Ton Duc Thang University, Ho Chi Minh City, Vietnam

• Full Professor, UNSW School of Public Health and Community Medicine, UNSW Australia

• Full Professor of Predictive Medicine, University of Technology, Sydney, Australia

• Principal Research Fellow, Head of Laboratory, Genetics and Epidemiology of Osteoporosis, Garvan Institute of Medical Research, Australia

Areas of expertise: Genomics, Genetics of Osteoporosis, Osteoporotic bone fractures, Bone strength, Bone fracture risk


• Editor:

Journal of Bone and Mineral Research

Osteoporosis international

Journal of Clinical Endocrinology and Metabolism

BMC Musculoskeletal Disorders

Journal of Clinical Densitometry


• Associate Editor:

BMC Research Notes

BMC Endocrine Disorders

Research track record (until 2021):

• ISI papers: >200

• Total ISI Citations: >16.000

• ISI H-index: 65

• Top ISI journals (at most 5):

1. Nature

2. British Medical Journal

3. New England Journal of Medicine

4. Lancet

5. Journal of the American Medical Association


Lan T. Ho-Pham, MD, MSc

Position: Co-director of Bone and Muscle Research Group, Ton Duc Thang University, Ho Chi Minh City, Vietnam

Areas of expertise: Osteoporosis, Osteoarthritis, Rheumatology, Nutrition, Epidemiology, Vitamin D, Bone Metabolism

Research track record (until October of 2015):

• ISI papers: 16

• Total ISI Citations: 350

• ISI H-index: 10

• Top ISI journals (at most 5):

1. Journal of Clinical Endocrinology and Metabolism

2. American Journal of Clinical Nutrition

3. Bone

4. Osteoporosis International

5. Calcified Tissue International

5. Publications (ISI or Scopus only)

20. Huy G. Nguyen, Nghi V. Le, Khang H. Nguyen-Duong, Lan T. Ho-Pham, Tuan V. Nguyen (2021); Reference values of body composition parameters for Vietnamese men and women; European Journal of Clinical Nutrition (ISI).

19. Duy K. Hoang,Nhan M. Le,Uyen P. Vo-Thi,Huy G. Nguyen,Lan T. Ho-Pham,Tuan V. Nguyen (2021); Mechanography assessment of fall risk in older adults: the Vietnam Osteoporosis Study; Journal of Cachexia, Sarcopenia and Muscle (ISI).

18. Duy K. Hoang,Minh C. Doan,Linh D. Mai,Thao P. Ho-Le,Lan T. Ho-Pham (2021), Burden of osteoporosis in Vietnam: An analysis of population risk; PLoS ONE (ISI).

17. Lan T. Ho-Pham, Minh C. Doan, Long H. Van & Tuan V. Nguyen (2020); Development of a model for identification of individuals with high risk of osteoporosis; Archives of Osteoporosis (ISI).

16. Lan T. Ho-Pham, Bich Tran, An T. Do, Tuan V. Nguyen (2019); Association between pre-diabetes, type 2 diabetes and trabecular bone score: The Vietnam Osteoporosis Study; Diabetes Research and Clinical Practice (ISI).

15. L. T. Ho-Pham & T. V. Nguyen (2019); Association between trabecular bone score and type 2 diabetes: a quantitative update of evidence; Osteoporosis International(ISI).

14. L.T. Ho-Pham, P.M.N. Chau, A.T. Do, H.C. Nguyen, T.V. Nguyen (2018); Type 2 diabetes is associated with higher trabecular bone density but lower cortical bone density: the Vietnam Osteoporosis Study ; Osteoporosis International (ISI).

13. Lan T. Ho-Pham, Thao P. Ho-Le, Linh D. Mai, Tam M. Do, Minh C. Doan & Tuan V. Nguyen (2018); Sex-difference in bone architecture and bone fragility in Vietnamese ; Scientific Reports (ISI).

12. Lich T Nguyen, Vinh N Pham, Phuong M N Chau, Lan T Ho-Pham, Tuan V Nguyen (2018); Association between carotid intima-media thickness and bone mineral density: a cross-sectional study in Vietnamese men and women aged 50 years and older ; BMJ Open (ISI).

11. Lan T. Ho-Pham ,Uyen D. T. Nguyen, Truong X. Tran,Tuan V. Nguyen (2017); Discordance in the diagnosis of diabetes: Comparison between HbA1c and fasting plasma glucose ; Plos One (ISI).

10. Lan T.Ho-Pham, Didier Han, Minh C.Doan, Linh D.Mai, Tuan V.Nguyen (2016); Genetic determinant of trabecular bone score (TBS) and bone mineral density: A bivariate analysis ; Bone (ISI).

9. Lan T. Ho-Pham, Thai Q. Lai, Uyen D. T. Nguyen, Quoc V. Bui,Tuan V. Nguyen (2017); Delineating the Relationship Between Leptin, Fat Mass, and Bone Mineral Density: A Mediation Analysis ; Calcified Tissue International (ISI).

8. L.T. Nguyen, U.D.T. Nguyen, T.D.T. Nguyen, L.T. Ho-Pham, T.V. Nguyen (2018); Contribution of bone turnover markers to the variation in bone mineral density: a study in Vietnamese men and women; Osteoporosis International (ISI).

7. Lan T. Ho-Pham, Thanh T. Do, Lesley V. Campbell, Tuan V. Nguyen; HbA1c-Based Classification Reveals Epidemic of Diabetes and Prediabetes in Vietnam; Diabetes Care, Volume 39 (2016), Pages e93-e94 (ISI).

6. Lan T. Ho-Pham, Thai Q. Lai, Linh D. Mai, Minh C. Doan, Tuan V. Nguyen; Body Composition in Individuals with Asymptomatic Osteoarthritis of the Knee; Calcified Tissue International, Volume 98 (2016), Pages 165-171 (ISI).

5. Lan T. Ho-Pham, Thai Q. Lai, Linh D. Mai, Minh C. Doan, Hoa N. Pham, Tuan V. Nguyen; Prevalence and Pattern of Radiographic Intervertebral Disc Degeneration in Vietnamese: A Population-Based Study; Calcified Tissue International, DOI: 10.1007/s00223-015-9986-4 (2015) (ISI).

4. Lan T. Ho-Pham, Sing C. Nguyen, Bich Tran, Tuan V. Nguyen; Contributions of Caucasian-associated bone mass loci to the variation in bone mineral density in Vietnamese population; Bone, In Press (2015) (ISI).

3. Lan T. Ho-Pham, Thai Q. Lai, Linh D. Mai, Minh C. Doan, Hoa N. Pham, Tuan V. Nguyen; Prevalence of Radiographic Osteoarthritis of the Knee and Its Relationship to Self-Reported Pain; PLOS ONE, DOI: 10.1371/journal.pone.0094563 (2014) (ISI).

2. Lan T. Ho-Pham, Uyen D. T. Nguyen, and Tuan V. Nguyen; Association between lean mass, fat mass, and bone mineral density: A meta-analysis; The Journal of Clinical Endocrinology & Metabolism, Vol. 99, Issue 1 (2014) (ISI).

1. Lan T Ho-Pham, Nguyen D Nguyen and Tuan V Nguyen; Quantification of the relative contribution of estrogen to bone mineral density in men and women; BMC Musculoskeletal Disorders, 14:366 (2013) (ISI).

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